Pharma & Biopharma
Computational R&D support for pharmaceutical and biopharma organisations, from early target identification and hit discovery through ADMET profiling, lead optimisation and clinical data analytics.
How 7DNA Supports Pharma R&D
Target Identification & Validation
Network pharmacology approaches integrating PPI networks, pathway databases and disease gene datasets to identify and prioritise drug targets. Computational docking validation of target-ligand interactions.
Learn moreVirtual Screening & Hit Discovery
In silico high-throughput virtual screening of chemical libraries against validated protein targets. Molecular docking, pharmacophore screening and ligand-based similarity searching to identify candidate hits.
Learn moreADMET Profiling
In silico ADMET prediction for candidate compounds, Lipinski / Veber drug-likeness, solubility, permeability, hERG toxicity, CYP inhibition prediction and blood-brain barrier penetration using validated computational models.
Learn moreBiomarker Discovery
Multi-omics integration and statistical analysis to identify disease biomarkers and pharmacodynamic markers from genomics, transcriptomics and proteomics datasets, relevant for companion diagnostics and patient stratification.
Learn moreClinical Data Analytics
Statistical analysis of clinical trial data, survival analysis, efficacy endpoint modelling, subgroup analysis and biostatistics reporting for regulatory submissions.
Learn moreDrug Response Prediction
ML-based prediction of drug response from molecular profiles, integrating genomic, transcriptomic and epigenomic data to build models applicable to patient stratification and precision medicine.
Learn moreComputational Expertise Grounded in Biology
Unlike general-purpose IT or data science consultancies, 7DNA's team has domain training in medicinal chemistry, molecular biology and pharmacology. We understand the biology behind the computation.
- ✓Structure-based drug design, not just number-crunching
- ✓Appropriate tool selection for each stage of the discovery pipeline
- ✓Results interpreted in biological and pharmacological context
- ✓Publication-ready reports and data packages
Primary Tools
Databases
Deliverable Formats
Ready to accelerate your drug discovery pipeline?
Tell us about your target, compound libraries or analytical challenge, we'll scope a computational approach.